Pharmaceutical composition for diseases caused by...

C - Chemistry – Metallurgy – 07 – K

Patent

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167/139, 195/1.1

C07K 16/18 (2006.01) A61K 39/395 (2006.01) C07K 16/26 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2008122

ABSTRACT OF THE DISCLOSURE A pharmaceutical composition comprising an anti- endothelin antibody as an effective component is disclosed. The antibody inhibits constrictions caused by endothelins in aorta and basilar, coronary, and kidney arteries. The composition is useful for curing diseases caused by vasoconstriction such as hypertension, coronary artery contracture, basilar artery contracture, and asthma.

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