Pharmaceutical composition for inhibiting platelet aggregation

A - Human Necessities – 61 – K

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A61K 31/55 (2006.01)

Patent

CA 2087743

There is disclosed a pharmaceutical composition for inhibiting platelet aggregation comprising 5-(2-chlorobenzyl)-4,5,6,7- tetrahydrothieno[3,2-c]pyridine or a pharmaceutically acceptable salt thereof and a 1,5-benzothiazepine derivative of the formula: Image wherein R1 is a lower alkyl group or a lower alkoxy group, R2 is a lower alkanoyl group, R3 and R4 are a lower alkyl group and R5 is hydrogen atom, a lower alkyl group or a halogen atom, or a pharmaceutically acceptable salt thereof.

L'invention porte sur une composition pharmaceutique pour inhiber l'agrégation plaquettaire, constituée de 5-(2-chlorobenzyl)-4,5,6,7-tétrahydrothiéno¢3,2-c!pyridine ou d'un sel pharmacocompatible de ce composé, et d'un dérivé de 1,5-benzothiazépine - de formule Image , dans laquelle R1 est un alkyle ou un alcoxy inférieurs, R2 est un alcanoyle inférieur, R3 et R4 sont un groupe alkyle inférieur et R5 est un atome d'hydrogène, un alkyle inférieur ou un halogène -, ou un sel pharmacocompatible de ce dérivé.

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