Pharmaceutical composition for prevention and treatment of...

A - Human Necessities – 61 – K

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A61K 31/4965 (2006.01)

Patent

CA 2740570

The present invention relates to a pharmaceutical composition for the prevention and treatment of diabetes or obesity comprising as active ingredients a compound which inhibits the activity of dipeptidyl peptidase-IV(DPP-IV), a pharmaceutically acceptable salt thereof, a hydrate thereof, or a solvate thereof, and one or more other antidiabetic or antiobesity agents. The pharmaceutical composition exhibits excellent glucose tolerance and may be useful in the prevention and treatment of diabetes, obesity, and the like by effectively inhibiting blood glucose levels and reducing fat mass.

L'invention concerne une composition pharmaceutique ou un médicament pour la prévention et le traitement de diabètes ou de l'obésité comprenant comme principe actif un composé, un sel pharmaceutiquement acceptable de celui-ci ou un hydrate ou une solution de celui-ci, qui inhibe DPP-IV. Ayant une excellente tolérance au glucose, ladite composition pharmaceutique peut servir pour traiter les diabètes et l'obésité et pour contrôler effectivement les niveaux de glycémie et réduire la quantité de gras.

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