A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4035 (2006.01) A61P 3/06 (2006.01)
Patent
CA 2565878
[PROBLEMS] To provide a pharmaceutical composition for the prevention or treatment of lipid metabolism disorder. [MEANS FOR SOLVING PROBLEMS] There is provided a pharmaceutical composition comprising, as an active ingredient, (2S)-2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl)propionic acid(common name: mitiglinide) or its pharmacologically acceptable salt, or a hydrate thereof. This pharmaceutical composition exerts a striking lipid metabolism improving effect, so that it is useful for, for example, hyperlipemia, such as hypertriglyceridemia, of diabetic patients.
[PROBLÈMES] Fournir une composition pharmaceutique pour la prévention ou le traitement de maladies liées au métabolisme des lipides. [RÉSOLUTION DES PROBLÈMES] Il est fourni une composition pharmaceutique comprenant, en tant que principe actif, de l~acide (2S)2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl)propionique (nom commun : mitiglinide) ou son sel acceptable du point de vue pharmacologique, ou un hydrate de celui-ci. Cette composition pharmaceutique exerce un effet remarquable améliorant le métabolisme des lipides, le rendant utile pour, par exemple, l~hyperlipidémie, comme l~hypertriglycéridémie de patients diabétiques.
Fukuyama Juichi
Yamada Masayuki
Kirby Eades Gale Baker
Kissei Pharmaceutical Co. Ltd.
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