A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/665 (2006.01) A61K 9/08 (2006.01) A61K 33/12 (2006.01) A61M 1/16 (2006.01)
Patent
CA 2129509
TITLE OF THE INVENTION Pharmaceutical composition for renal disorder and a dialysis solution for extracorporeal hemodialysis ABSTRACT OF THE INVENTION A pharmaceutical composition for renal disorder and a dialysis solution for extracorporeal hemodialysis which comprise a phosphoric acid diester of the following formula: Image (wherein R1 and R2 are the same or different and each represents a hydrogen atom or a methyl group) or a pharmacologically acceptable salt thereof. Since the composition of this invention inhibits the formation of free radicals in the body, it can be advantageously used for the prophylaxis and treatment of various renal disorders such as glomerulonephritis, acute renal failure, uremia, adriamycin nephrosis, puromycin nephrosis, gentamicin- and cisplatin-induced disorders of the kidney, renal impairment due to paraquat and other agricultural chemicals, and immune complex nephritis. Moreover, the composition of this invention is also of use as a dialysis solution for extracorporeal hemodialysis with the propylactic/therapeutic effect on dialysis amyloidosis.
Matsuura Sachiko
Nagao Rie
Ogata Kazumi
Ogino Shinya
Saito Noriko
Kirby Eades Gale Baker
Senju Pharmaceutical Co. Ltd.
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