Pharmaceutical composition for the treatment of acute disorders

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/16 (2006.01) A61K 31/196 (2006.01) A61K 31/341 (2006.01) A61K 31/4439 (2006.01) A61K 38/22 (2006.01)

Patent

CA 2345121

A pharmaceutical composition for the treatment of acute disorders is described. The composition comprises an essentially water-free, ordered mixture of at least one pharmaceutically active agent in the form of microparticles which are adhered to the surfaces of carrier particles which are substantially larger than the particles of the active agent or agents, and are essentially water-soluble, in combination with the bioadhesion and/or mucoadhesion promoting agent. The invention also relates to a method for preparing the composition and to the use of the composition for the treatment of acute disorders.

L'invention porte sur une composition pharmaceutique destinée à traiter les maladies aiguës. Cette composition comprend un mélange ordonné, essentiellement exempt d'eau, d'au moins un agent actif se présentant sous forme de microparticules collées aux surfaces des particules porteuses qui sont bien plus grosses que celles de l'agent ou des agents actif(s), et qui sont principalement solubles dans l'eau en combinaison avec un agent favorisant la bioadhésion et/ou la mucoadhésion. Cette invention porte également sur un procédé de préparation de la composition et sur l'utilisation de la composition dans le traitement des maladies aiguës.

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