Pharmaceutical composition for topical use containing a...

A - Human Necessities – 61 – K

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A61K 47/32 (2006.01) A61K 8/35 (2006.01) A61K 8/36 (2006.01) A61K 8/368 (2006.01) A61K 8/39 (2006.01) A61K 8/42 (2006.01) A61K 8/73 (2006.01) A61K 8/81 (2006.01) A61K 8/86 (2006.01) A61K 8/896 (2006.01) A61K 47/00 (2006.01) A61K 47/34 (2006.01) A61Q 19/00 (2006.01) A61Q 19/04 (2006.01) A61Q 19/10 (2006.01)

Patent

CA 2141192

The present invention relates to pharmaceutical compositions for topical application comprising a safe and effective amount of a pharmaceutical active, from about 0.1 % to about 10.0 % of a high molecular weight cationic polymer, from about 0.05 % to about 5 % of a high HLB non-ionic surfactant, and from about 0.1 % to about 25 % of an alkoxylated ether. In further embodiments, these compositions also comprise from about 0.01 % to about 5 % of a low HLB non-toxic surfactant.

L'invention concerne des compositions pharmaceutiques à application topique comprenant une quantité sûre et efficace d'un ingrédient actif pharmaceutique, d'environ 0,1 à environ 10,0 % d'un polymère cationique de poids moléculaire élevé, d'environ 0,05 à environ 5 % d'un surfactant non ionique au rapport hydro-lipophile élevé et d'environ 0,1 à environ 25 % d'un éther alcoxylé. Dans d'autres versions, ces compositions comprennent également d'environ 0,01 à environ 5 % d'un surfactant non toxique au rapport hydro-lipophile faible.

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