Pharmaceutical composition for treatment of immunological...

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01)

Patent

CA 2556739

Disclosed is a pharmaceutical composition for treating immunological disorders by inhibiting the activation of T lymphocytes, comprising, as active ingredients, two or more selected from the group consisting of a substance capable of blocking binding of an MHC (Major Histocompatibility Complex) Class II molecule and a receptor thereof, a substance capable of blocking binding of a costimulatory molecule and a receptor thereof a substance capable of blocking binding of an adhesion molecule and a receptor thereof, and a substance capable of blocking binding of a cytokine and a receptor thereof.

L'invention porte sur une composition pharmaceutique destinée à être utilisée dans le traitement de troubles immunologiques en inhibant l'activité des lymphocytes T et comprenant, comme ingrédients actifs, au moins deux éléments sélectionnés dans le groupe comprenant une substance capable de bloquer la liaison d'une molécule de la classe II du CMH (complexe majeur d'histocompatibilité) et un récepteur de celle-ci, une susbtance capable de bloquer la liaison d'une molécule costimulatoire et d'un récepteur de celle-ci, une substance capable de bloquer la liaison d'une molécule d'adhésion et d'un récepteur de celle-ci et une susbtance capable de bloquer la liaison d'une cytokine et d'un récepteur de celle-ci.

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