Pharmaceutical composition for use for the treatment of...

A - Human Necessities – 61 – K

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A61K 31/663 (2006.01) A61K 31/196 (2006.01) A61K 31/335 (2006.01) A61K 31/337 (2006.01) A61K 31/365 (2006.01) A61K 31/415 (2006.01) A61K 31/42 (2006.01) A61K 31/444 (2006.01) A61K 31/635 (2006.01) A61K 31/66 (2006.01) A61K 45/06 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2461085

A pharmaceutical composition for treatment of malignancies, in particular a malignant disease which is associated with the development of bone metastases or excessive bone resorption, comprises in combination a bisphosphonates, COX- 2 inhibitor and/or a taxol or derivative thereof for simultaneous, sequential or separate use. Also provided is a method of treating a patient suffering from a malignant disease comprising administering to the patient an effective amount of a bisphosphonates, an effective amount of a COX-2 inhibitor and/or and effective amount of a taxol or derivative thereof.

Composition pharmaceutique servant à traiter des tumeurs malignes, en particulier, une malignité associée au développement de métastases osseuses ou d'une résorption osseuse excessive et contenant une combinaison de biphosphonate, d'inhibiteur de COX-2 et/ou d'un taxol ou d'un dérivé de ce dernier afin de les utiliser de façon simultanée, consécutive ou séparée. Procédé de traitement d'un patient atteint par une malignité et consistant à administrer à ce patient une quantité efficace de biphosphonate, une quantité efficace d'un inhibiteur de COX-2 et/ou une quantité efficace d'un taxol ou d'un dérivé de taxol.

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