Pharmaceutical composition including ace/nep inhibitors and...

Details Pharmaceutical composition including ace/nep inhibitors and... Pharmaceutical composition including ace/nep inhibitors and...

A - Human Necessities

61

K

A61K 47/12 (2006.01) A61K 9/48 (2006.01) A61K 31/197 (2006.01) A61K 31/198 (2006.01) A61K 31/343 (2006.01) A61K 31/357 (2006.01) A61K 31/40 (2006.01) A61K 31/554 (2006.01) A61K 47/20 (2006.01) A61K 47/22 (2006.01) A61K 47/28 (2006.01)

Patent

CA 2445860

A pharmaceutical composition comprising an inhibitor of angiotensin converting enzyme and neutral endopeptidase, such as sampatrilat, and at least one bioavailability enhancer such as an organic acid, e.g., ascorbic acid. Such a composition has improved systemic bioavailability.

L'invention porte sur une préparation pharmaceutique comprenant un inhibiteur de l'enzyme de conversion de l'angiotensine et de l'endopeptidase neutre, par exemple le sampatrilat, et un renforcateur de biodisponibilité par exemple un acide organique, tel que l'acide ascorbique. Cette préparation renforce la biodisponibilité systémique.

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