A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 51/00 (2006.01) A61P 35/00 (2006.01) C07B 59/00 (2006.01) C07C 231/12 (2006.01) C07F 5/00 (2006.01)
Patent
CA 2736237
Provided is a pharmaceutical composition comprising radioiodinated N-(2- (diethylamino)ethyl)-4-(4-fluorobenzamido)-5-iodo-2-methoxybenzamide of Formula I. The pharmaceutical composition provides a stable formulation for both storing and administering to patients having melanoma. Also provided is a novel method of iodinating the precursor compound.
La présente invention concerne une composition pharmaceutique comprenant du N-(2-(diéthylamino)éthyl)-4-(4-fluorobenzamido)-5-iodo-2-méthoxybenzamide radioiodé de formule I. Cette composition pharmaceutique constitue une formulation stable pouvant être stockée et administrée à des patients souffrant d'un mélanome. L'invention concerne également un procédé inédit d'iodation du composé précurseur.
Babich John W.
Chen Jianqing
Kronauge James F.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Molecular Insight Pharmaceuticals Inc.
LandOfFree
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