A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/32 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 31/215 (2006.01) A61K 31/216 (2006.01) A61K 31/22 (2006.01)
Patent
CA 2219475
FENOFIBRATE PHARMACEUTICAL COMPOSITION DEMONSTRATING A HIGH BIO-AVAILABILITY, AND ITS METHOD OF PREPARATION // The invention relates to an immediate-release fenofibrate composition comprising: (a) an inert water-soluble base covered with at least one layer containing a fenofibrate active substance in micronized form no more than 20 µm, a hydrophilic polymer, and possibly a surfactant, said hydrophilic polymer accounting for at least 20% of the weight of element (a), with (b) possibly one or several phases or external layers. The method of preparation of the composition also represents part of the invention.
L'invention a pour objet une composition de fénofibrate à libération immédiate comprenant: (a) un support inerte hydrosoluble recouvert d'au moins une couche contenant un principe actif fénofibrate sous forme micronisée une taille inférieure à 20 µm, un polymère hydrophile et éventuellement un tensio-actif; ledit polymère hydrophile représentant au moins 20% en poids du poids de l'élément a); et (b) éventuellement une ou plusieurs phase(s) ou couche(s) externe(s). L'invention a encore pour objet son procédé de préparation.
Seth Pawan
Stamm Andre
Laboratoires Fournier S.a.
Robic
LandOfFree
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