Pharmaceutical composition of vinflunine which is intended...

A - Human Necessities – 61 – K

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A61K 31/4375 (2006.01) A61K 9/08 (2006.01) A61K 47/12 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2551493

The invention relates to a pharmaceutical composition of vinflunine in the form of a stable sterile aqueous solution of a water-soluble salt of vinflunine with a pH of between 3 and 4. The invention also relates to the method of preparing said composition and to the use thereof as a parenterally-administered medicament for the treatment of cancer.

La présente invention concerne une composition pharmaceutique de vinflunine se présentant sous la forme d'une solution aqueuse stable et stérile d'un sel hydrosoluble de vinflunine à un pH compris entre 3 et 4. Elle concerne également le procédé de préparation de cette composition et son utilisation en tant que médicament destiné à une administration parentérale dans le traitement du cancer.

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