A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/187
A61K 47/38 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 31/43 (2006.01)
Patent
CA 1338467
A pharmaceutical tablet is provided containing an amphoteric beta-lactam antibiotic, microcrystalline or microfine cellulose or a mixture of both and a second disintegrant, being low-substituted hydroxypropylcellulose which fully disintegrates in water within 60 seconds. When swallowed it shows a bioavailability as good as a pharmacy prepared suspenison of the antibiotic. The tablet is compressed from a mixture containing a new granulate which is prepared from the antibiotic substance, microcrystalline and/or microfine cellulose and water only. Such tablets can also be prepared by using other know tablet disintegrants as the second disintegrant.
560356
Akkerboom Piet Johannes
de Boer Leonardus Wilhelmus Theodorus
Olthoff Margaretha
Astellas Pharma Europe B.v.
Osler Hoskin & Harcourt Llp
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