Pharmaceutical composition using aliskiren and avosentan

Details Pharmaceutical composition using aliskiren and avosentan Pharmaceutical composition using aliskiren and avosentan

A - Human Necessities

61

K

A61K 31/165 (2006.01) A61K 31/506 (2006.01) A61P 9/08 (2006.01) A61P 13/12 (2006.01)

Patent

CA 2673391

The present invention relates to a pharmaceutical composition and method of achieving a therapeutic effect including, but not limited to, the treatment of hypertension, kidney or heart disease in an animal, preferably a mammal including a human subject, using (i) SPP100/aliskiren or a pharmaceutically acceptable salt thereof in combination with (ii) SPP301/avosentan or a pharmaceutically acceptable salt thereof and (iii) a pharmaceutically acceptable carrier.

L'invention concerne une composition pharmaceutique et un procédé qui permettent d'obtenir un effet thérapeutique tel que, de manière non limitative, le traitement de l'hypertension, d'une maladie rénale ou cardiaque chez un animal, de préférence un mammifère, y compris un sujet humain, au moyen (i) de l'aliskirène/SPP100 ou d'un sel pharmaceutiquement acceptable de ce dernier combiné à (ii) de l'avosentan/SPP301 ou à un sel pharmaceutiquement acceptable de ce dernier et (iii) à un véhicule pharmaceutiquement acceptable.

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