A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/14 (2006.01) A61K 9/48 (2006.01) A61K 31/19 (2006.01) A61K 31/192 (2006.01) A61K 31/22 (2006.01) A61K 31/222 (2006.01) A61K 47/20 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2247520
The invention concerns a pharmaceutical composition with base of rhein or diacerhein. The composition is designed for oral, rectal or cutaneous (percutaneous or transdermal) administration, and contains rhein or diacerhein, or one of their pharmaceutically acceptable salts or esters, and sodium laurylsulphate, co-micronized in a weight ratio ranging between 3:1 and 30:1. The composition has improved biological availability.
L'invention concerne une composition pharmaceutique à base de rhéine ou de diacérhéine. La composition est destinée à une administration par voie orale, rectale ou cutanée (percutanée ou transdermique), et comprend de la rhéine ou de la diacérhéine, ou un de leurs sels ou esters pharmaceutiquement acceptables, et du laurysulfate de sodium, comicronisés, dans un rapport en poids compris entre 3:1 et 30:1. La composition présente une biodisponibilité améliorée.
Estanove Cyril
Prudhomme Alain
Mazal Pharmaceutique (s.a.r.l.)
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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