A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01) A61K 31/135 (2006.01) A61K 31/485 (2006.01)
Patent
CA 2714921
Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided.
L'invention propose une composition pharmaceutique qui comporte un antagoniste, un agoniste, un enrobage de scellement et un polymère séquestrant, l'antagoniste, l'agoniste, l'enrobage de scellement et au moins un polymère séquestrant étant tous des composants d'une seule unité, et l'enrobage de scellement formant une couche séparant physiquement l'un de l'autre l'antagoniste de l'agoniste. L'invention propose également des procédés de fabrication d'une telle composition pharmaceutique.
Jones James
Liang Alfred
Stauffer Joseph
Alpharma Inc.
Ridout & Maybee Llp
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