Pharmaceutical compositions

C - Chemistry – Metallurgy – 08 – B

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C08B 37/16 (2006.01) A61K 31/19 (2006.01) A61K 31/715 (2006.01) A61K 47/48 (2006.01)

Patent

CA 1320192

A B S T R A C T PHARMACEUTICAL COMPOSITIONS Complexes of B-cyclodextrin with various salts of ibuprofen are described in which the molar ratios of ibuprofen to B-cyclodextrin are within the range of from 1:0.20 to 1:0.75. The preferred salt of ibuprofen is the sodium salt. The complexes have enhanced taste profile and bioavailability. Also disclosed are methods for preparing the complexes and also pharmaceutical compositions thereof.

600940

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