Pharmaceutical compositions

Details Pharmaceutical compositions Pharmaceutical compositions

C - Chemistry, Metallurgy

07

D

167/127, 530/5.0

C07D 213/69 (2006.01) A61K 31/295 (2006.01) A61K 31/40 (2006.01) C07D 307/62 (2006.01) C07D 309/40 (2006.01) C07F 15/02 (2006.01)

Patent

CA 1286844

ABSTRACT PHARMACEUTICAL COMPOSITIONS Iron complexes comprising a ferric cation in combination with at least two different ligands, at least one of which is provided by a compound being: (1) 3-hydroxy-4-pyrone or a 3-hydroxy-4-pyrone in which one or more of the hydrogen atoms attached to ring carbon atoms are replaced by an aliphatic hydrocarbon group of 1 to 6 carbon atoms; (2) a 3-hydroxypyrid-2-one or 3-hydroxypyrid-4-one in which the hydrogen atom attached to the nitrogen atom is replaced by a formyl or aliphatic hydrocarbyl-carbonyl group, by an aliphatic hydrocarbon group of 1 to 6 carbon atoms, or by an aliphatic hydrocarbon group substituted by one or more substituents selected from formyl, aliphatic hydrocarbyl- carbonyl, alkoxy, aliphatic amide, formyloxy, aliphatic hydrocarbyl-carbonyloxy, aliphatic hydrocarbyl-oxycarbonyl, aliphatic hydrocarbyl-sulphonyloxy, aliphatic hydrocarbyl- oxysulphonyl, halogen and hydroxy groups and, optionally, in which one or more of the hydrogen atoms attached to ring carbon atoms are replaced by one of said substituents, by an aliphatic hydrocarbon group of 1 to 6 carbon atoms, or by an aliphatic hydrocarbon group substituted by an alkoxy, formyloxy, aliphatic hydrocarbyl-carbonyloxy, aliphatic hydrocarbyl-oxycarbonyl, aliphatic hydrocarbyl-sulphonyloxy, aliphatic hydrocarbyl- oxysulphonyl, halogen or hydroxy group; or (3) an alternative compound providing a physiologically acceptable, monobasic, bidentate ligand which is capable of binding covalently to iron that either contains a first grouping which is an enolic hydroxy group or a carboxy group and a second grouping which is an amine group or a hydroxy group, or is a monocarboxylic acid providing an anion containing a grouping Image , but with the proviso that at least one of the ligands is of type (1) or (2); are of value in medicine, particularly in the treatment of iron deficiency anaemia.

479100

Affiliated with

Also associated with

Rating

Pharmaceutical compositions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical compositions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical compositions will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1206903