C - Chemistry – Metallurgy – 08 – B
Patent
C - Chemistry, Metallurgy
08
B
C08B 37/00 (2006.01) A61K 9/127 (2006.01) A61K 47/46 (2006.01) A61K 47/48 (2006.01)
Patent
CA 2109952
Polysaccharides comprising at least 5 sialic acid residues per molecule and used to increase the circulation time, decrease the immunogenicity and/or increase the stability in vivo of pharmaceutically active compounds. The pharmaceutically active compound may be a foreign protein which is covalently bound to the polysaccharide. Alternatively the active compound may be associated with a drug delivery system (DDS), for instance a macro-molecular DDS or a particulate DDS, such as liposomes. The polysaccharide is usually a bacterial polysaccharide, e.g. a glycolipid or a derivative thereof, for instance polysaccharide B or E. Coli K1, N.meningitidis, Moraxella liquifaciens or Pasteurella aeroginosis, or K92 of E. Coli K92 strain.
Borden Ladner Gervais Llp
Lipoxen Technologies Limited
The School Of Pharmacy University Of London
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