Pharmaceutical compositions

A - Human Necessities – 61 – K

Patent

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167/180

A61K 31/43 (2006.01) A61K 9/48 (2006.01) A61K 31/545 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01) A61K 47/14 (2006.01)

Patent

CA 2003340

RAN 4600/60 ABSTRACT The absorption of antibiotics given through oral and rectal routes of administration is significantly enhanced by use of the antibiotic in conjunction with a two-component absorption enhancing system made up of an ether of a C6 to C18 alcohol and a polyoxyethylene glycol together with a second component selected from among polyoxyethylene glycol- C6 to C18 glyceride esters, C6 to C18 carboxylic acids or salts thereof, and esters of two or more C6 to C18 carboxylic acids, glycerol and a polyoxyethylene glycol. A carrier and adjuvants are usually included. These compositions can be administered in any convenient oral or rectal dosage form, including tablets, capsules, beadlets and suppositories.

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