A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/107 (2006.01) A61K 31/055 (2006.01) A61K 31/436 (2006.01) A61K 31/55 (2006.01) A61K 47/10 (2006.01)
Patent
CA 2200966
This invention provides a topical composition, in the form of an emulsion, that comprises a compound of the FK506 class; a physiologically acceptable alkanediol, ether diol or diether alcohol containing up to 8 carbon atoms as solvent for the compound of the FK506 class; an unsaturated fatty alcohol and water. In another aspect, this invention provides a topical pharmaceutical composition that comprises a macrolide in suspension. In a further aspect, this invention provides the use of an unsaturated fatty alcohol to stabilise a macrolide in a pharmaceutical composition.
Composition topique sous forme d'émulsion, comportant un composé de la classe FK506; un alcanediol, diol d'éther ou alcool de diéther physiologiquement acceptable ayant jusqu'à 8 atomes de carbone et servant de solvant pour le composé de la classe FK506; un alcool gras insaturé et de l'eau. On a également prévu une composition pharmaceutique topique comportant un macrolide en suspension. En outre, on a prévu l'utilisation d'un alcool gras insaturé dans le but de stabiliser un macrolide dans une composition pharmaceutique.
Jackman Martin
Popp Xue-Ping
Richter Friedrich
Schmook Fritz
Kirby Eades Gale Baker
Novartis Ag
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