A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/46 (2006.01) A61K 31/40 (2006.01) A61P 3/00 (2006.01) A61P 3/06 (2006.01) A61P 9/00 (2006.01) A61K 45/06 (2006.01)
Patent
CA 2676352
The present invention relates to a CCR5 antagonist compound for elevating high density lipoprotein (HDL) particles in a patient, improving plasma lipid profile in a patient or reducing triglycerides in a patient. The invention also relates to a pharmaceutical composition comprising a CCR5 antagonist compound, an HMG-CoA reductase inhibitor compound and a pharmaceutically acceptable carrier. The invention also relates to a pharmaceutical composition comprising a CCR5 antagonist compound, a cholesteryl ester transfer protein (CETP) inhibitor compound and a pharmaceutically acceptable carrier.
La présente invention porte sur un composé antagoniste CCR5 pour augmenter les particules de lipoprotéine de haute densité (HDL) dans un patient, améliorer le profil lipidique dans le plasma d'un patient ou réduire les triglycérides dans un patient. L'invention porte également sur une composition pharmaceutique comprenant un composé antagoniste CCR5, un composé inhibiteur de HMG-CoA réductase et un support pharmaceutiquement acceptable. L'invention porte également sur une composition pharmaceutique comprenant un composé antagoniste CCR5, un composé inhibiteur de la protéine de transfert d'ester cholestérylique (CETP) et un support pharmaceutiquement acceptable.
Felstead Stephen John
Hopkins Andrew Lee
Mayer Howard Bernard
Mchale Mary
Limited Pfizer
Smart & Biggar
LandOfFree
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