A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4535 (2006.01)
Patent
CA 2553428
The invention relates to a pharmaceutical composition comprising i) ketotifen or an analog thereof and ii) a chemotherapeutic drug subject to multi-drug resistance by P-gp, such as doxorubicin or an analog thereof. The pharmaceutical composition is useful for treating cancer. The pharmaceutical composition is also useful for i) preventing or treating multi-drug resistance in a subject or ii) preventing a chemotherapeutic drug subject to multi-drug resistance by P-gp induced cardiac tissue damage in a subject, such as doxorubicin or an analog thereof. The invention relates to a pharmaceutical composition comprising i) ketotifen or an analog thereof and ii) a chemotherapeutic drug subject to multi-drug resistance by P-gp, such as doxorubicin or an analog thereof. The pharmaceutical composition is useful for treating cancer. The pharmaceutical composition is also useful for i) preventing or treating multi-drug resistance in a subject or ii) preventing a chemotherapeutic drug subject to multi-drug resistance by P-gp induced cardiac tissue damage in a subject, such as doxorubicin or an analog thereof.
L'invention concerne une composition pharmaceutique comprenant i) du kétotifène ou un analogue de celui-ci et ii) un médicament chimiothérapeutique pouvant faire l'objet d'une résistance pléiotrope due à la P-gp, tel que la doxorubicine ou un analogue de celle-ci. Cette composition pharmaceutique peut être utilisée pour le traitement du cancer. Elle est également utile pour i) empêcher ou traiter la résistance pléiotrope chez un patient ou ii) empêcher, chez un patient, un endommagement du tissu cardiaque induit par un médicament chimiothérapeutique pouvant faire l'objet d'une résistance pléiotrope due à la P-gp, tel que la doxorubicine ou un analogue de celle-ci.
Berger Stuart A.
Zhang Yicheng
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
University Health Network
LandOfFree
Pharmaceutical compositions and methods for treating... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pharmaceutical compositions and methods for treating..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical compositions and methods for treating... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2045574