A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/195
A61K 31/575 (2006.01) A61K 31/565 (2006.01) C07J 13/00 (2006.01) C07J 31/00 (2006.01) C07J 41/00 (2006.01)
Patent
CA 2001790
The use of fusidic acid or a derivative thereof for the manufacture of a composition for interfering with cytokines in a biological system, in particular for interfering with a cytokine such as e lymphokine, interleukin, monokine, interferon or colony-stimulating factor. Fusidic acid and derivatives thereof are useful for preventing ef- fects of cytokines known to be pathogenetically involved in patholo- gical conditions. Said conditions may e.g. be: Insulin-dependent diabetes mellitus (type 1), hyper- or hypo- functioning of the thyroid gland (e.g. thyroiditis), Addison's di- sease, endogenous uveitis, eye surgery such as cornea transplanta- tion, cataract operation and laser surgery, transplant rejection, graft-verses-host disease, Crohn's disease or ulcerative colitis, pernicious anemia, celiac disease, contact dermatitis, allergic/ato- pic dermatitis, pemphigus vulgaris or pemphigoid, multiple sclerosis, systemic lupus erythematosus, polymyalgia rheumatica, conditions related to vasculitis phenomena, neoplastic diseases such as multiple myeloma, septic shock caused by gram-negative bacteria, DIC, arterio- sclerosis, periodontal diseases, arthritis, osteoarthrosis or ar- thritis urica.
Bendtzen Klaus
Mccarthy Tetrault Llp
LandOfFree
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