Pharmaceutical compositions as inhibitors of dipeptidyl...

C - Chemistry – Metallurgy – 07 – C

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C07C 211/40 (2006.01) A61K 31/137 (2006.01) C07C 211/54 (2006.01) C07C 211/62 (2006.01) C07D 213/38 (2006.01) C07D 213/68 (2006.01) C07D 317/64 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2617495

The present invention relates to compounds, which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, metabolic syndrome , hyperinsulinemia, obesity, atherosclerosis, various immunomodulatory diseases, and other diseases.

Cette invention concerne des composés qui inhibent la dipeptidyl peptidase IV (DPP-IV) et qui sont utilisés pour prévenir ou traiter le diabète, en particulier le diabète de type II, ainsi que l'hyperglycémie, le syndrome métabolique, l'hyperinsulinémie, l'obésité, l'athérosclérose, diverses maladies immunomodulatrices et autres maladies.

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