Pharmaceutical compositions based on diclofenac derivate

A - Human Necessities – 61 – K

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Details

A61K 9/18 (2006.01) A61K 9/16 (2006.01) A61K 31/216 (2006.01) A61P 29/00 (2006.01) C07C 201/10 (2006.01)

Patent

CA 2529963

The present invention relates to particles comprising the drug 2-[2- (nitrooxy)ethoxy]ethyl {2-[(2,6-dichlorophenyl)amino]phenyl}acetate, optionally mixed with one or more surfactant(s) and to a new drug delivery composition comprising said particles optionally in combination with a second drug. Furthermore, the invention relates to processes for preparing said particles and drug delivery composition as well as the use of said composition in the manufacturing of a medicament.

La présente invention concerne des particules comprenant le médicament 2-[2-(nitrooxy)éthoxy]éthyl {2-[(2,6-dichlorophényl)amino]phényl}acétate, éventuellement mélangé avec un ou plusieurs tensioactifs, et une nouvelle composition d'administration de ce médicament comprenant lesdites particules, éventuellement en combinaison avec un second médicament. De plus, l'invention concerne des procédé de fabrication desdites particules et de la composition d'administration du médicament ainsi que l'utilisation de ladite composition pour la fabrication du médicament.

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