A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/24 (2006.01) A61K 9/00 (2006.01) A61K 47/12 (2006.01)
Patent
CA 2330500
The invention concerns fluid pharmaceutical compositions for controlled release of at least one active substance comprising: a) a therapeutically efficient amount of at least one active substance; b) 3 to 55 wt. % of phospholipid; c) 16 to 72 wt. % of one or several pharmaceutically acceptable solvents; and d) 4 to 52 wt. % of at least one fatty acid. Said composition is characterised in that it has the property of being instantaneously gelled in the presence of an aqueous phase. The invention also concerns methods for preparing said compositions and their use for treating a human being or animal.
L'invention se rapporte à des compositions pharmaceutiques fluides permettant la libération contrôlée d'au moins une substance active comprenant: a) une quantité thérapeutiquement efficace d'au moins une substance active, b) de 3 à 55 % en poids de phospholipide, c) de 16 à 72 % en poids d'un ou plusieurs solvants pharmaceutiquement acceptables, et d) de 4 à 52 % en poids d'au moins un acide gras, ladite composition ayant la propriété de se gélifier instantanément en présence d'une phase acqueuse. Elle concerne égalemt des procédés de préparation de ces compositions et leur utilisation pour le traitement d'une personne ou d'un animal.
Deleers Michel
Fanara Domenico
Vranckx Henri
Robic
Ucb S.a.
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