Pharmaceutical compositions comprising...

A - Human Necessities – 61 – K

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A61K 31/135 (2006.01) C07C 211/42 (2006.01)

Patent

CA 2260037

Pharmaceutical compositions for the treatment of a neurological disorder or neurotrauma or for improving memory in a patient, comprising a therapeutically effective amount of S-(-)-N-propargyl-1- aminoindan or a pharmaceutically acceptable salt thereof as active ingredient, and a pharmaceutically active carrier. The pharmaceutical compositions are adapted, in particular for treating a neurological disorder or neurotrauma involving damage caused to the central or peripheral nervous system as a result of ischemic damage, stroke, hypoxia or anoxia, neurodegenerative diseases, Parkinson's Disease, Alzheimer's Disease, neurotoxic injury, head trauma injury, spinal trauma injury or any other form of nerve damage.

Compositions pharmaceutiques pour le traitement de pathologies neurologiques ou de traumatismes nerveux ou encore pour l'amélioration des capacités mnésiques d'un patient. Lesdites compositions comportent une quantité efficace du point de vue thérapeutique de s-(-)-n-propargyl-1-aminoindane ou tout sel pharmaceutiquement acceptable dudit élément comme ingrédient actif et un transporteur pharmacologiquement actif. Ces compositions pharmaceutiques servent en particulier pour le traitement des pathologies neurologiques ou pour les traumatismes nerveux impliquant des dommages causés au système nerveux central ou périphérique par suite d'une lésion d'origine ischémique, d'un choc nerveux, d'hypoxémie ou d'anoxie, des maladies neurodégénératives, des maladies de Parkinson et d'Alzheimer, d'accidents neurotoxiques, de traumatismes crânien et spinal ou de toute autre forme de dommage nerveux.

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