C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/22 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) A61P 37/00 (2006.01) C07D 215/16 (2006.01) C07D 215/233 (2006.01) C07D 215/26 (2006.01) C07D 215/32 (2006.01) C07D 215/38 (2006.01) C07D 401/06 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 491/08 (2006.01)
Patent
CA 2381968
The invention concerns a non-cytotoxic pharmaceutical composition acting on the proliferation of clonogenic cells in malignant tumours and comprising an efficient amount of a compound selected among the compounds of formula (I) and (Ia) wherein: R¿1?, R¿2?, R¿3?, R¿4?, R¿5?, R¿6? and R¿6a?are as defined in claim 1.
La présente invention concerne une composition pharmaceutique non cytotoxique ayant une activité sur la prolifération de cellules clonogènes dans les tumeurs malignes et qui comprend une quantité efficace d'un composé choisi parmi les composés de formules (I) et (Ia) dans laquelle R1, R2, R3, R4, R5, R6 et R6a sont tels que définis à la revendication 1.
Darro Francis
Frydman Armand
Guillaumet Gerald
Joseph Benoit
Kiss Robert
Fetherstonhaugh & Co.
Laboratoire L. Lafon
LandOfFree
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