A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/505 (2006.01) A61K 9/10 (2006.01) A61K 47/40 (2006.01) A61P 25/00 (2006.01) A61P 25/06 (2006.01) A61P 25/08 (2006.01)
Patent
CA 2367040
A pharmaceutical composition comprising a) a 1,2,4-triazolo(1,5-a)pyrimidine derivative of formula (I) including pharmaceutically acceptable salts, racemates, enantiomers, diastereoisomers and mixtures thereof, b) a cyclodextrin. These compositions are useful in the treatment of migraine, seizures and/or neurological disorders such as epilepsy and/or as neuroprotective agents to protect against conditions such as stroke, brain trauma, head injuries and haemorrhage in animals including human beings.
Cette invention a trait à une composition pharmaceutique contenant: (a) un dérivé de pyrimidine 1,2,4-triazolo[1,5-a] de formule (I), y compris les sels, solvates, racémates, énantiomères et diastéréoisomères de ce dérivé ainsi que leurs mélanges, et (b) une cyclodextrine. Ces compositions se révèlent des plus utiles pour traiter la migraine, les attaques et/ou des troubles neurologiques tels que l'épilepsie et/ou en tant qu'agents neuroprotecteurs contre des états pathologiques tels que les accidents cérébrovasculaires, les lésions cérébrales, les blessures à la tête ainsi que les hémorragies et ce, tant chez les humains que chez les animaux.
Heal David John
Kilpatrick Ian Charles
Martin Keith Frank
Smith Sharon Lesley
Knoll Gmbh
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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