Pharmaceutical compositions comprising a soluble laminin...

A - Human Necessities – 61 – K

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A61K 38/00 (2006.01) A61K 38/17 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2291720

The present invention relates to pharmaceutical compositions comprising a soluble laminin receptor precursor (LRP) or a modification thereof. The present invention also relates to pharmaceutical compositions comprising a compound which blocks the interaction of LRP and PrPsc or PrPsc. Said compositions allow the treatment of diseases associated with the presence of PrPsc. In addition, the present invention provides an expression vector for the recombinant production of LRP or any other kind of protein in the baculovirus system.

La présente invention concerne des compositions pharmaceutiques comprenant un précurseur de récepteur de laminine soluble (LRP) ou une modification de ce dernier. La présente invention concerne également des compositions pharmaceutiques comprenant un composé qui bloque l'interaction de LRP avec PrPS?c¿ ou PrP?c¿. Ces compositions sont destinées au traitement d'affections associées à la présence de PrPS?c¿. La présente invention concerne en outre un vecteur d'expression destiné à la production par recombinaison de LRP ou de tout autre type de protéine dans le système de baculovirus.

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