Pharmaceutical compositions comprising active vitamin d...

A - Human Necessities – 61 – K

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A61K 31/59 (2006.01) A61K 9/107 (2006.01) A61K 31/355 (2006.01)

Patent

CA 2528552

Disclosed are pharmaceutical compositions comprising an active vitamin D compound in emulsion pre-concentrate formulations, as well as emulsions and sub-micron droplet emulsions produced therefrom. The compositions comprise a lipophilic phase component, one or more surfactants, and an active vitamin D compound. The compositions may optionally further comprise a hydrophilic phase component.

L'invention a trait à des compositions pharmaceutiques contenant un composé actif de vitamine D, qui se présentent sous la forme de préconcentrés d'émulsions, ainsi qu'à des émulsions et des émulsions à gouttelettes submicroniques produites à partir desdites compositions. Les compositions selon l'invention contiennent un composant de phase lipophile, un ou plusieurs tensioactifs, et un composé actif de vitamine D. Les compositions peuvent également contenir éventuellement un composant de phase hydrophile.

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