Pharmaceutical compositions comprising an hydrogenated ergot...

Details Pharmaceutical compositions comprising an hydrogenated ergot... Pharmaceutical compositions comprising an hydrogenated ergot...

A - Human Necessities

61

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167/116, 167/199

A61K 31/495 (2006.01) A61K 31/48 (2006.01) C07D 209/32 (2006.01) C07D 215/20 (2006.01) C08B 37/10 (2006.01) C07D 519/02 (2006.01)

Patent

CA 1224416

ABSTRACT Novel pharmaceutical compositions comprising i) an hydro- genated ergot alkaloid having vaso-constrictor activity, for example dihydroergotamine, or a pharmaceutically accep- table acid addition salt thereof and ii) a low molecular weight heparin or pharmaceutically acceptable salt thereof, and process for their production. Components ii) suitably have an average molecular weight of less than 10,000. The compositions are especially useful in the prevention of post-operative thrombosis.

442829

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