Pharmaceutical compositions comprising cetp inhibitors and a...

A - Human Necessities – 61 – K

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A61K 31/265 (2006.01)

Patent

CA 2519432

The invention provides pharmaceutical compositions comprising a cholesteryl ester transfer protein (CETP) inhibitor and a water-insoluble concentration- enhancing additive, which exhibit improved bioavailability. The invention also provides methods of treating cardiovascular disorders comprising the administration of the pharmaceutical compositions comprising a CETP inhibitor.

Cette invention se rapporte à des compositions pharmaceutiques comprenant un inhibiteur de protéine de transfert de cholestéryl-ester (CETP) et un additif d'amélioration de concentration insoluble dans l'eau, qui possèdent une biodisponibilité améliorée. Cette invention concerne également des procédés pour traiter des troubles cardio-vasculaires, consistant à administrer ces compositions pharmaceutiques comprenant un inhibiteur de CETP.

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