Pharmaceutical compositions comprising monoamine oxidase b...

A - Human Necessities – 61 – K

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Details

A61K 31/135 (2006.01) A61K 9/00 (2006.01) A61K 31/136 (2006.01) A61K 31/137 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2214026

This invention relates to a pharmaceutical composition for oral administration comprising a carrier and, as an active ingredient, a monoamine oxidase B inhibitor, characterised in that the composition is formulated to promote pre-gastric absorption of said monoamine oxidase B inhibitor. A process for preparing such a composition and the use of such a composition for the treatment of Parkinson's disease, the treatment and/or prophylaxis of depression and the treatment and/or prophylaxis of Alzheimer's disease are also provided.

Composition pharmaceutique pouvant être administrée par voie orale et comportant un excipient et, à titre d'ingrédient actif, un inhibiteur de monoamine-oxydase B. Cette composition est formulée de manière à favoriser l'absorption prégastrique dudit inhibiteur de monoamine-oxydase B. On a également prévu un procédé de préparation d'une composition de ce type, ainsi que l'utilisation de cette composition dans le traitement de la maladie de Parkinson, dans le traitement et/ou la prévention de la dépression, et dans le traitement et/ou la prévention de la maladie d'Alzheimer.

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