A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/353 (2006.01) A61K 9/20 (2006.01) A61K 47/34 (2006.01) A61P 9/12 (2006.01)
Patent
CA 2675538
The disclosed pharmaceutical compositions for oral administration comprising as the active medicinal ingredient nebivolol, a nebivolol analogue or a pharmaceutically acceptable acid addition salt thereof and a wetting agent. The ratio of the wetting agent to the active ingredient is less than 0.025. The application also relates to methods of preparing these compositions and using said compositions for treating coronary vascular disorders in humans.
L'invention porte sur des compositions pharmaceutiques pour une administration orale comprenant, en tant que principe médicinal actif, du nébivolol, un analogue du nébivolol ou un sel pharmaceutiquement acceptable d'addition d'acide de ceux-ci et un agent mouillant. Le rapport de l'agent mouillant sur le principe actif est inférieur à 0,025. L'invention porte également sur des procédés de préparation de ces compositions et sur l'utilisation desdites compositions pour traiter des troubles vasculaires coronariens chez les êtres humains, notamment l'hypertension.
Akbarieh Mostafa
Mohideen Fazal M.
Shah Shetal
Genpharm Ulc
Mylan Pharmaceuticals Ulc
Osler Hoskin & Harcourt Llp
LandOfFree
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