Pharmaceutical compositions comprising nep-inhibitors,...

Details Pharmaceutical compositions comprising nep-inhibitors,... Pharmaceutical compositions comprising nep-inhibitors,...

A - Human Necessities

61

K

A61K 31/55 (2006.01) A61K 31/366 (2006.01) A61K 31/40 (2006.01) A61K 45/06 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2590278

A novel combination therapy is described for cardiovascular diseases or conditions, by administering a synergistic combination of at least one inhibitor of neutral endopepti- dase, at least one inhibitor of the endogenous endothelin producing system and at least one HMG CoA reductase inhibitor.

L'invention porte sur une nouvelle thérapie combinatoire s'appliquant aux maladies ou états cardio-vasculaires, cette méthode thérapeutique consistant à administrer une combinaison synergique d'au moins un inhibiteur de l'endopeptidase neutre, au moins un inhibiteur du système produisant l'endothéline endogène et au moins un inhibiteur de la réductase HMG CoA.

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