Pharmaceutical compositions comprising old man's beard...

A - Human Necessities – 61 – K

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A61K 36/09 (2006.01) A61K 8/97 (2006.01) A61K 36/38 (2006.01) A61P 17/02 (2006.01) A61Q 19/08 (2006.01)

Patent

CA 2563870

The invention relates to pharmaceutical compositions from Usnea barbata and their use in the treatment of skin diseases. A preferred composition is the combination with an extract from Hypericum perforatum. The extracts are obtained by hypercritical high-pressure extraction with natural carbonic acid. A preferred method of production is the common homogenization of 6 % by weight of an extract from Usnea barbata, containing 96 % usnic acid, and 40 % by weight of an extract from Hypericum perforatum, containing 39 % hyperforin. The pharmaceutical composition brings about an exponentiation of the anti- inflammatory and antimicrobial effects of the extracts and stabilizes the hyperforin. The combination is suitable for external and internal treatment of various skin diseases, especially various forms of dermatitis, and skin aging, and for the treatment of skin infections with Pityrosporon yeast fungi, acne and rosacea.

L'invention concerne des compositions pharmaceutiques composées d'usnée barbata et leur utilisation pour traiter des maladies de la peau. Une composition préférée est une association avec un extrait d'hypericum perforatum. Les extraits sont obtenus par extraction haute pression surcritique avec du gaz carbonique de la source. Une forme de production préférée est l'homogénéisation commune de 6 % en poids d'un extrait d'usnée barbata contenant 96 % d'acide usnique, et 40 % en poids d'un extrait d'hypericum perforatum contenant 39 % d'hyperforine. La composition pharmaceutique entraîne une forte augmentation des effets antiinflammatoires et antimicrobiens des extraits et à une stabilisation de l'hyperforine. Cette association convient au traitement externe et interne de différentes maladies de la peau, notamment d'inflammations cutanées et du vieillissement cutané, et au traitement d'infections cutanées à une levure le pityrosporon -, de l'acnée et de la couperose.

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