A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/28 (2006.01) A61K 9/00 (2006.01) A61K 9/107 (2006.01) A61K 31/485 (2006.01) A61K 47/14 (2006.01) A61K 47/30 (2006.01) A61P 3/10 (2006.01) A61K 47/22 (2006.01) A61K 47/32 (2006.01)
Patent
CA 2451839
A pharmaceutical composition comprising: (A) a continuous liquid phase; (B) liquid droplets dispersed in said continuous phase; (C) a pharmaceutically- active compound; (D) an enhancer as described in U.S. Patent No. 5,023,252; and (E) a hydrocolloid emulsifying agent; including, for example, a composition in which the liquid phase comprises an aqueous solution of insulin and the liquid droplets comprise a solution of the enhancer and a solvent therefore; and the use of the composition to treat a condition for example diabetes in a patient by applying to the membrane of the patient the composition.
La présente invention concerne une composition pharmaceutique comportant: (A) une phase liquide continue; (B) des gouttelettes de liquides dispersées dans ladite phase continue; (C) un composé pharmaceutiquement actif; (D) un agent d'activation tel que décrit dans le brevet U.S. No. 5023252; et (E) un agent émulsifiant d'hydrocolloïde; y compris, par exemple, une composition dans laquelle la phase liquide comporte une solution aqueuse d'insuline et les gouttelettes comporte une solution de l'agent d'activation et un solvant à cet effet. L'invention concerne également l'utilisation de la composition pour le traitement d'une condition pathologique, par exemple le diabète chez un patient par l'application de la composition à la membrane du patient.
Bentley Pharmaceuticals Inc.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Cpex Pharmaceuticals Inc.
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