Pharmaceutical compositions comprising phosphate-binding...

Details Pharmaceutical compositions comprising phosphate-binding... Pharmaceutical compositions comprising phosphate-binding...

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 31/785 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2749397

The present invention discloses pharmaceutical composition comprising phosphate binding polymers such as Sevelamer carbonate substantially free of monovalent anion other than bicarbonate anion. Particularly, monovalent anion content is less than about 0.05% (w/w). Disclosed are compositions comprising wet granulated Sevelamer carbonate free of added metal ions and/or added monovalent anion source.

La présente invention concerne une composition pharmaceutique qui comprend des polymères liant le phosphate tel que le carbonate Sevelamer sensiblement dépourvue d'anions monovalents autres qu'un anion bicarbonate. La teneur en anions monovalents est notamment inférieure à environ 0,05% (p/p). La présente invention concerne des compositions de carbonate Sevelamer soumises à une granulation par voie humide sans ions métalliques ajoutés et/ou source d'anions monovalents ajoutée.

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