A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 31/4745 (2006.01) A61K 38/04 (2006.01) A61K 47/36 (2006.01) A61P 35/04 (2006.01)
Patent
CA 2457056
The present invention is directed to a pharmaceutical composition for inhibiting the metastasis or preventing the recurrence of a malignant tumor, which comprises as the active ingredient a polysaccharide derivative comprising a polysaccharide having a carboxyl group bound to an active substance having an anti-tumor activity via an amino acid or a peptide consisting of 2 to 8 amino acids which are the same or different, or a salt thereof. Preferred active substances are camptothecin derivatives.
L'invention concerne une composition pharmaceutique permettant d'inhiber les métastases ou de prévenir la récurrence d'une tumeur maligne. Cette composition comprend en tant que principe actif un dérivé de polysaccharide composé d'un polysaccharide comprenant un groupe carboxyle lié a un composant actif à activité antitumorale par l'intermédiaire d'un acide aminé ou d'un peptide comprenant de 2 à 8 acides aminés identiques ou différents, ou un sel de ce composé. Les principes actifs préférés sont des dérivés de camptothécine.
Kawaguchi Takayuki
Okuno Satoshi
Yano Toshiro
Kirby Eades Gale Baker
Mitsubishi Tanabe Pharma Corporation
Tanabe Seiyaku Co. Ltd.
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