Pharmaceutical compositions comprising synthetic peptide...

Details Pharmaceutical compositions comprising synthetic peptide... Pharmaceutical compositions comprising synthetic peptide...

A - Human Necessities

61

K

A61K 38/16 (2006.01) A61K 31/785 (2006.01) C08G 69/10 (2006.01)

Patent

CA 2215389

Pharmaceutical compositions comprising as active ingredient a synthetic random copolymer of average molecular weight of about 4,000-12,000, preferably 6,000- 8,000, said copolymer consisting of glutamic acid (Glu), lysine (Lys), alanine (Ala) and tyrosine (Tyr) residues in a relative molar ratio of 1.4-2.1 parts of Glu to 3.2-5.0 parts of Lys to 4.0-6.6 parts of Ala to 1.0 parts of Tyr (herein GLAT copolymers), can be used in a method for prevention and treatment of graft-versus-host disease in patients in the course of bone marrow and organ transplantation.

L'invention porte sur des compositions pharmaceutiques comportant comme principe actif un copolymère aléatoire de synthèse, du type GLAT, d'un poids moléculaire moyen d'environ 4 000 à 12 000 et de préférence de 6 000 à 8 000, consistant en groupes d'acide glutamique (Glu), de lysine (Lys), d'alanine (Ala) et de tyrosine (Tyr) dans un rapport molaire relatif de 1,4 à 2,1 parties de Glu, de 3,2 à 5,00 parties de Lys, de 4,0 à 6,6 parties d'Ala et de 1,0 parties de Tyr. Ladite composition peut servir à la prévention et au traitement de troubles dus à la réaction greffe contre hôte chez des patients subissant des transplantations de moelle ou d'organes.

Affiliated with

Also associated with

Rating

Pharmaceutical compositions comprising synthetic peptide... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical compositions comprising synthetic peptide..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical compositions comprising synthetic peptide... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1903043