C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 205/04 (2006.01) A61K 31/397 (2006.01) A61P 25/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01)
Patent
CA 2400138
The invention concerns pharmaceutical compositions containing as active ingredient a compound of formula (I) wherein: R¿1? represents a -NHCOR¿4? or -N(R¿5?)-Y-R¿6? radical; Y is CO or SO¿2?; R¿4? represents an -alk-SO¿2?R¿11?, -alk-SO¿2?-CH=CH-R¿11?, Het substituted by -SO¿2?R¿11? or phenyl substituted by -SO¿2?-R¿11? or -alk-SO¿2?-R¿11? radical; R¿5? represents a hydrogen atom or an alkyl radical; R¿6? represents a phenylalkyl radical, Het or Ar; the novel derivatives of formula (I) and their preparation.
La présente invention concerne des compositions pharmaceutiques contenant comme ingrédient actif un composé de formule(I) dans laquelle R1 représente un radical -NHCOR4 ou -N(R5)-Y-R6, Y est CO ou SO2, R4 représente un radical -alk- SO2-R11, -alk-SO2-CH=CH-R11, Het substitué par -SO2-R11 ou phényle substitué par -SO2-R11 ou -alk-SO2-R11, R5 représente un atome d'hydrogène ou un radical alkyle, R6 représente un radical phénylalkyle, Het ou Ar, les nouveaux dérivés de formule (I) et leur préparation.
Achard Daniel
Bouchard Herve
Bouquerel Jean
Filoche Bruno
Grisoni Serge
Aventis Pharma S.a.
Robic
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