Pharmaceutical compositions containing active agents having...

Details Pharmaceutical compositions containing active agents having... Pharmaceutical compositions containing active agents having...

A - Human Necessities

61

K

A61K 31/4745 (2006.01) A61K 9/127 (2006.01) A61K 9/51 (2006.01) A61K 47/02 (2006.01)

Patent

CA 2527130

Compositions and methods for stabilizing an active agent containing one or more actone rings. The compositions, including pharmaceutical compositions, ensure that the lactone ring of the active agent is stabilized in the active, ring-closed form due to the inclusion of a transition metal ion.

Cette invention se rapporte à des compositions et à des procédés servant à stabiliser un agent actif contenant un ou plusieurs cycles de lactone. Ces compositions, qui sont également des compositions pharmaceutiques, assurent que le cycle de lactone de l'agent actif soit stabilisé dans la forme active à cycle fermé, en raison de l'inclusion d'un ion de métaux de transition.

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