Pharmaceutical compositions containing an effervescent...

A - Human Necessities – 61 – K

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Details

A61K 9/46 (2006.01) A61K 31/137 (2006.01) A61K 31/195 (2006.01) A61K 31/5415 (2006.01)

Patent

CA 2297673

A pharmaceutical composition in form of effervescent tablets comprising an active ingredient and an effervescent blend, wherein the effervescent blend comprises an acidic component and sodium glycine carbonate as alkaline components. Preferred acid component are fumaric acid, maleic acid and their salts. Tablets are prepared by direct compression in normal thermo-hygrometric conditions and with standard tabletting equipment.

Cette invention concerne une composition pharmaceutique se présentant sous forme de comprimés effervescents comprenant un principe actif et un mélange effervescent, ce mélange effervescent comprenant un constituant acide et du carbonate de glycine de sodique en tant que constituant alcalin. Le constituant acide préféré peut être l'acide fumarique, l'acide maléique ainsi que leurs sels. Les comprimés sont préparés par compression directe dans des conditions de chaleur et d'hygrométrie normales et avec du matériel de production de comprimés standard.

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