Pharmaceutical compositions containing camptothecins

Details Pharmaceutical compositions containing camptothecins Pharmaceutical compositions containing camptothecins

A - Human Necessities

61

K

A61K 31/4745 (2006.01) A61K 47/02 (2006.01) A61K 47/20 (2006.01) A61K 47/22 (2006.01)

Patent

CA 2503099

A camptothecin-containing pharmaceutical composition which contains: (a) camptothecin or a derivative thereof, and (b) one or more compounds selected from among ascorbic acid or a salt thereof, sodium hydrogen sulfite, sodium sulfite, potassium pyrosulfite, sodium erythorbate, sodium thioglycolate, sodium pyrosulfite, and .alpha.-thioglycerin. The pharmaceutical composition is useful in that, after storage for a long period of time or under light-irradiation conditions, camptothecin or a derivative thereof contained therein undergoes minimum degradation.

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