A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 9/19 (2006.01) A61K 31/4745 (2006.01) A61K 47/10 (2006.01) A61K 47/26 (2006.01) A61K 47/36 (2006.01) C07D 491/22 (2006.01)
Patent
CA 2415922
Pharmaceutical compositions which contain compounds obtained by bonding a carboxyl-bearing polysaccharide derivative to a camptothecin derivative either through a spacer or not therethrough and are improved in storage stability by the addition of a sugar or a sugar alcohol and, if necessary, a pH regulator.
L'invention concerne des compositions pharmaceutiques qui renferment des composés obtenus par liaison d'un dérivé polysaccharide porteur de carboxyle à un dérivé camptothécine par le biais ou non d'un espaceur. On améliore leur stabilité en stockage par l'adjonction d'un sucre ou d'un alcool de sucre et, s'il y a lieu, d'un régulateur de pH.
Sugie Shuichi
Takahashi Masayuki
Takeuchi Masahito
Daiichi Pharmaceutical Co. Ltd.
Riches Mckenzie & Herbert Llp
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