Pharmaceutical compositions containing fluorinated or...

A - Human Necessities – 61 – K

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A61K 31/20 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) G01N 33/50 (2006.01) G01N 33/92 (2006.01)

Patent

CA 2438085

Fluorinated or perfluorinated carboxylic acids are useful in treating diabetes, obesity, hypercholesterolaemia, cancer, inflammation or other conditions in which modulation of lipid or eicosanoid status or function may be desirable.

Les molécules de la formule (I) Z?1¿-X-X?2¿ sont utiles pour traiter le diabète, l'obésité, l'hypercholestérolémie, l'hyperlipidémie, le cancer, les inflammations ou d'autres états dans lesquels une modulation de l'état ou de la fonction des lipides ou des éicosanoïdes peut être souhaitable. Dans ladite formule Z?1¿ représente -CO¿2?H ou un dérivé de celui-ci; Z?2¿ représente F, H, -CO¿2?H ou un dérivé; et X représente alklyène fluoré; ou un solvate de ceux-ci, par exemple un acide gras perfluoré ou son dérivé.

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