Pharmaceutical compositions containing nanocapsules

Details Pharmaceutical compositions containing nanocapsules Pharmaceutical compositions containing nanocapsules

A - Human Necessities

61

K

A61K 9/51 (2006.01) A61K 9/10 (2006.01) A61K 31/727 (2006.01) A61K 38/22 (2006.01) B01J 13/14 (2006.01) A61K 31/725 (1990.01)

Patent

CA 2113243

A pharmaceutical composition in the form of a colloidal suspension of nanocapsules, comprising an oily phase consisting essentially of an oil containing dissolved therein a surfactant and suspended therein a plurality of nanocapsules having a diameter of less than 500 nanometers, said nanocapsules encapsulating an aqueous phase consisting essentially of a solution or a suspension of a therapeutically active substance, a surfactant and optionally ethanol; a process for preparing the said composition is also described. The walls of said nanocapsules are formed from a poly(alkyl 2-cyanoacrylate) wherein the alkyl radical has 1 to 6 carbon atoms. This composition is particularly suitable for oral administration of polypeptides and polysaccharides.

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